ABSTRACT
The emergence and spread of SARS-CoV-2 have threatened the world’s public health security. The COVID-19 pandemic has affected many countries and significantly smashed the global economy, and also affected the health of the environment. This has upraised many apprehensions about its high transmission rate. Even though the most important routes of its transmission include direct contact and respiratory droplets, the infection through non-direct contacts also plays an important role. The increasing demand for intensive healthcare, escalating death toll and disruption in supply chains and trade have directed to mass implementation of testing, quarantine, and lockdown to restrain virus transmission. The lockdown has been a boon and a bane as well when it comes to the health of the environment. It had improved the air and water quality since the industrial activities were banned and therefore there was no addition of pollutants in the environment, but the usage of plastic-based personal protective equipment (PPE) and other medical waste has simultaneously resulted in huge plastic pollution that is choking seas and marine lives. The precautionary measures given by the United Nations Environment Programme in its COVID response factsheets suggest ways to reduce medical waste and to prevent the spread of the present pandemic. The recent green innovations and environmental stringency programs have resulted in reducing the threats to the environment that would eventually help in inhibiting the spread of such pandemics. In addition, proper measures should be adopted to safeguard the complete health of humans and the environment to execute safety and sustainable development that will help in achieving a stable biome. Graphical
ABSTRACT
Biological polyesters of hydroxyacids are known as polyhydroxyalkanoates (PHA). They have proved to be an alternative, environmentally friendly and attractive candidate for the replacement of petroleum-based plastics in many applications. Many bacteria synthesize these compounds as an intracellular carbon and energy compound usually under unbalanced growth conditions. Biodegradability and biocompatibility of different PHA has been studied in cell culture systems or in an animal host during the last few decades. Such investigations have proposed that PHA can be used as biomaterials for applications in conventional medical devices such as sutures, patches, meshes, implants, and tissue engineering scaffolds as well. Moreover, findings related to encapsulation capability and degradation kinetics of some PHA polymers has paved their way for development of controlled drug delivery systems. The present review discusses about bio-plastics, their characteristics, examines the key findings and recent advances highlighting the usage of bio-plastics in different medical devices. The patents concerning to PHA application in biomedical field have been also enlisted that will provide a brief overview of the status of research in bio-plastic. This would help medical researchers and practitioners to replace the synthetic plastics aids that are currently being used. Simultaneously, it could also prove to be a strong step in reducing the plastic pollution that surged abruptly due to the COVID-19 medical waste.